HIF1A
表示
(HIF-1αから転送)
HIF1Aはヘテロ二量体として構成される低酸素誘導因子HIF-1のうちHIF-1αサブユニットをコードしている遺伝子。[5][6][7]
脚注
[編集]- ^ a b c GRCh38: Ensembl release 89: ENSG00000100644 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021109 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ “Assignment of the hypoxia-inducible factor 1alpha gene to a region of conserved synteny on mouse chromosome 12 and human chromosome 14q”. Genomics 34 (3): 437–9. (June 1996). doi:10.1006/geno.1996.0311. PMID 8786149.
- ^ “Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway”. J. Biol. Chem. 272 (13): 8581–93. (March 1997). doi:10.1074/jbc.272.13.8581. PMID 9079689.
- ^ “Entrez Gene: HIF1A hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)”. 2017年10月10日閲覧。
参考文献
[編集]- “HIF-1 and human disease: one highly involved factor”. Genes Dev. 14 (16): 1983–91. (2000). PMID 10950862.
- “Signal transduction to hypoxia-inducible factor 1”. Biochem. Pharmacol. 64 (5–6): 993–8. (2002). doi:10.1016/S0006-2952(02)01168-1. PMID 12213597.
- “Quiescent hypervascularity mediated by gain of HIF-1 alpha function”. Cold Spring Harb. Symp. Quant. Biol. 67: 133–42. (2002). doi:10.1101/sqb.2002.67.133. PMID 12858534.
- “Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors”. Nat. Rev. Immunol. 5 (9): 712–21. (2005). doi:10.1038/nri1685. PMID 16110315.
- “Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes”. Histol. Histopathol. 20 (4): 1327–38. (2005). PMID 16136514.
- “Hypoxia and HIF-1 alpha in chondrogenesis”. Semin. Cell Dev. Biol. 16 (4–5): 539–46. (2006). doi:10.1016/j.semcdb.2005.03.003. PMID 16144691.
- “Hypoxia-inducible factors in the kidney”. Am. J. Physiol. Renal Physiol. 291 (2): F271-81. (2006). doi:10.1152/ajprenal.00071.2006. PMID 16554418.
- “Effects of histone deacetylase inhibitors on HIF-1”. Cell Cycle 5 (21): 2430–5. (2006). doi:10.4161/cc.5.21.3409. PMID 17102633.