アクタプラニン

アクタプラニン
	別称 Antibiotic A 4696, Kamoran
識別情報
CAS登録番号	37305-75-2
PubChem	16132360
UNII	BIC0KCT1E9
	特記なき場合、データは常温 (25 °C)・常圧 (100 kPa) におけるものである。

アクタプラニン（英：Actaplanin）は、アクチノプラネス属細菌によって生成される広域抗生物質の複合体である^[1]^[2]。1984年にEli Lilly and Co.のグループによって行われた研究では、高速液体クロマトグラフィーを用いていくつかのアクタプラニンが同定された^[3]^[4]^[5]。アクタプラニンA、B₁、B₂、B₃、C₁、Gは、同じペプチドコア、アミノ糖、様々な量のグルコース、マンノース、ラムノースから構成されていることが示された^[6]。

脚注

^ Debono, Manuel; Merkel, Kurt E.; Molloy, R. Michael; Barnhart, Mitchell; Presti, Eugene; Hunt, Ann H.; Hamill, Robert L. (1984). “Actaplanin, new glycopeptide antibiotics produced by Actinoplanes missouriensis. The isolation and preliminary chemical characterization of actaplanin”. The Journal of Antibiotics 37 (2): 85–95. doi:10.7164/antibiotics.37.85. PMID 6706856.
^ Huber, Floyd M.; Pieper, Richard L.; Tietz, Anthony J. (January 1987). “Characterization of the process for the biosynthesis of the actaplanin complex by Actinoplanes missouriensis”. Journal of Fermentation Technology 65 (1): 85–89. doi:10.1016/0385-6380(87)90069-0.
^ Debono, Manuel; Merkel, Kurt E.; Molloy, R. Michael; Barnhart, Mitchell; Presti, Eugene; Hunt, Ann H.; Hamill, Robert L. (1984). “Actaplanin, new glycopeptide antibiotics produced by Actinoplanes missouriensis. The isolation and preliminary chemical characterization of actaplanin.”. The Journal of Antibiotics 37 (2): 85–95. doi:10.7164/antibiotics.37.85. PMID 6706856 25 December 2014閲覧。.
^ US 4115552, Robert L Hamill & Donald C Delong, "Factor A and B of antibiotic A-4696", published 19 Sep 1978, assigned to Eli Lilly And Company
^ US 4322406, Manuel Debono; Robert E. Weeks & Herald J. Cole, "Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1", published 30 Mar 1982, assigned to Eli Lilly And Company
^ Hunt, Ann H.; Elzey, Thomas K.; Merkel, Kurt E.; Debono, Manuel (February 1984). “Structures of the actaplanins”. The Journal of Organic Chemistry 49 (4): 641–645. doi:10.1021/jo00178a012.

[:0-1] Debono, Manuel; Merkel, Kurt E.; Molloy, R. Michael; Barnhart, Mitchell; Presti, Eugene; Hunt, Ann H.; Hamill, Robert L. (1984). “Actaplanin, new glycopeptide antibiotics produced by Actinoplanes missouriensis. The isolation and preliminary chemical characterization of actaplanin”. The Journal of Antibiotics 37 (2): 85–95. doi:10.7164/antibiotics.37.85. PMID 6706856.

[:1-2] Huber, Floyd M.; Pieper, Richard L.; Tietz, Anthony J. (January 1987). “Characterization of the process for the biosynthesis of the actaplanin complex by Actinoplanes missouriensis”. Journal of Fermentation Technology 65 (1): 85–89. doi:10.1016/0385-6380(87)90069-0.

[:2-3] Debono, Manuel; Merkel, Kurt E.; Molloy, R. Michael; Barnhart, Mitchell; Presti, Eugene; Hunt, Ann H.; Hamill, Robert L. (1984). “Actaplanin, new glycopeptide antibiotics produced by Actinoplanes missouriensis. The isolation and preliminary chemical characterization of actaplanin.”. The Journal of Antibiotics 37 (2): 85–95. doi:10.7164/antibiotics.37.85. PMID 6706856 25 December 2014閲覧。.

[:3-4] US 4115552, Robert L Hamill & Donald C Delong, "Factor A and B of antibiotic A-4696", published 19 Sep 1978, assigned to Eli Lilly And Company

[:4-5] US 4322406, Manuel Debono; Robert E. Weeks & Herald J. Cole, "Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1", published 30 Mar 1982, assigned to Eli Lilly And Company

[6] Hunt, Ann H.; Elzey, Thomas K.; Merkel, Kurt E.; Debono, Manuel (February 1984). “Structures of the actaplanins”. The Journal of Organic Chemistry 49 (4): 641–645. doi:10.1021/jo00178a012.

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